Producción intelectual del grupo Grupo de Investigación en Microbiología y Genética

2021

Glutathione-related genetic polymorphisms are associated with mercury retention and nephrotoxicity in gold-mining settings of a Colombian population

Mercury (Hg) vapor can produce kidney injury, where the proximal tubule region of the nephron is the main target of the Hg-induced oxidative stress. Hg is eliminated from the body as a glutathione conjugate. Thus, single nucleotide polymorphisms (SNPs) in glutathione-related ge...


Autor(es): Fernando Rondon.   Oscar Flórez-Vargas.   Luz Helena Sánchez Rodríguez.   Linda Rocha Muñoz.   Olga Marcela Medina Pérez.   Giovanna Rincón Cruz.  



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2021

Diagrammatic scales for the estimation of black node disease severity in common bean

The objective of this study was to design two diagrammatic scales for the evaluation of black node disease (Stagonosporopsis hortensis and Boeremia spp.) in common bean (Phaseolus vulgaris L.). The developed scales corresponded to logarithmic intervals (SADL) of seven levels and ...


Autor(es): Luz Nayibe Garzon.   Yuranis Miranda Montero.   Linda Rincón Rivera.  



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2021

Prodigiosin Production and Photoprotective/Antigenotoxic Properties in Serratia marcescens Indigenous Strains from Eastern Cordillera of Colombia

Serratia marcescens is a bacterial species that produces an antibacterial pigment (Prodigiosin) showing a wide adaptive response to environmental stresses. The study aimed to investigate Prodigiosin production in S. marcescens wild-type strains, as well as its relation to photopr...


Autor(es): Jorge Luis Fuentes.   José D. D. Cediel Becerra.   Jhon A. Suescun Sepulveda.  



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2020

ON BIRDS OF SANTANDER-BIO EXPEDITIONS, QUANTIFYING THE COST OF COLLECTING VOUCHER SPECIMENS IN COLOMBIA

Several scientific reasons support continuing bird collection in Colombia, a megadiverse country with modest science financing. Despite the recognized value of biological collections for the rigorous study of biodiversity, there is scarce information on the monetary costs of spec...


Autor(es): Enrique Arbelaez.   Daniela Villamizar.   Fernando Rondon.  



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2020

Induction of the SOS response of Escherichia coli in repair-defective strains by several genotoxic agents

DNA is exposed to the attack of several exogenous agents that modify its chemical structure, so cells must repair those changes in order to survive. Alkylating agents introduce methyl or ethyl groups in most of the cyclic or exocyclic nitrogen atoms of the ring and exocyclic oxyg...


Autor(es): Jorge Luis Fuentes.   Jorge Serment-Guerrero.   Viridiana Dominguez-Monroy.   Jenny Davila-Becerril.   Enrique Morales-Avila.  



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2020

Genetic Polymorphisms in Multispecific Transporters Mitigate Mercury Nephrotoxicity in an Artisanal and Small-Scale Gold Mining Community in Colombia

In artisanal and small?scale gold mining, occupational exposure to mercury (Hg) vapor is related to harmful effects on several organs, including the kidneys. We previously reported significantly increased levels of Hg in blood and urine despite normal kidney function in individua...


Autor(es): Fernando Rondon.   Oscar Flórez-Vargas.   Luz Helena Sánchez Rodríguez.   Linda Rocha Muñoz.   Olga Marcela Medina Pérez.   Giovanna Rincón Cruz.  



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2020

PIMA: A population informative multiplex for the Americas

We describe an ancestry-informative autosomal SNP multiplex designed to be a small-scale, flexible panel that can complement uniparental markers in assessing the American variability (i.e. pre-Colombian) found in contemporary indigenous American populations. This study centered o...


Autor(es): Fernando Rondon.   Gloria Liliana Porras Hurtado.   Julieta Henao Bonilla.   Angel Carracedo.   Silviene Oliveira.   Guillermo Barreto.   Vivian Nogueira Silbiger.   Carlos Alberto Isaza.   Lareu MV.   Lisbeth Borjas.  



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2019

Las plantas como fuente de compuestos fotoprotectores frente al daño en el ADN producido por la radiación ultravioleta

La fotoprotección es una estrategia preventiva y terapéutica frente al cáncer y el envejecimiento de la piel. En el presente trabajo se revisan los efectos biológicos adversos de la radiación ultravioleta, los conceptos básicos relevantes de la fotoprotección y los métodos para l...


Autor(es): Jorge Luis Fuentes.  



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2019

Photoprotective and antigenotoxic effects of the flavonoids apigenin, naringenin and pinocembrin

This work evaluated the photoprotective and antigenotoxic effects against ultraviolet B (UVB) radiation of flavonoid compounds apigenin, naringenin and pinocembrin. The photoprotective efficacy of these compounds was estimated using in vitro photoprotection indices, and the antig...


Autor(es): Adriana Garcia.   Diego Armando Villamizar.   Elena Stashenko.   Jorge Luis Fuentes.   Luis A. Núñez.   Raquel Elvira Ocazionez.  



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2018

Proteomic analysis reveals an extract of the plant Lippia origanoides suppresses mitochondrial metabolism in triple-negative breast cancer cells

Triple-negative breast cancer is an aggressive subtype of breast cancer with low 5-year survival rates, high 3-year recurrence rates, and no known therapeutic targets. Recent studies have indicated that triple-negative breast cancers possess an altered metabolic state with higher...


Autor(es): Jorge Luis Fuentes.   VISHAK RAMAN.   UMA K ARYAL.   VICTORIA HEDRICK.   RODRIGO MOHALLEM FERREIRA.   ELENA STASHENKO.   MORRIS LEVY.   MARIA M LEVY.   IGNACIO G CAMARILLO.  



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2018

Influence of the uvrA, recJ and recN gene mutations on the nucleoid reorganization in UV-treated Escherichia coli cells

Exposure to ultraviolet (UV) radiation blocks DNA replication and arrests cellular division in Escherichia coli. Restoration of chromosome replication involves nucleoid reorganization, which involves the participation of the recombination-catalyzing proteins RecA, RecO, RecR and ...


Autor(es): Carlos Felipe Estevez.   Jorge Luis Fuentes.   JORGE HUMBERTO SERMENT GUERRERO.  



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2018

Reproduction and community structure of fish from winter catch sites from industrial shrimp bycatch from the northeast and southeast Mexican Pacific

The shrimp fishery is one of the most important fisheries in the world, although the low selectivity from trawling nets has led to the capture of a large number of non-target species. Shrimp-bycatch species include a large number of fish and invertebrate species, of which fish sp...


Autor(es): Francisco Jose Martinez.   Jorge de Jesus Tirado-Ibarra.   Mariany Loya-Rodriguez.   Jose Carlos Morales-Arevalo.   Isabel Rosario Muñoz Garcia.   Jorge Saul Ramirez-Perez.   Laura Rebeca Jimenez-Gutierrez.  



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2018

On the Causes of Rapid Diversification in the Páramos: Isolation by Ecology and Genomic Divergence in Espeletia

How diversity arises and what is the relative role of allopatric and ecological divergence are among the most persistent questions in evolution and ecology. Here, we assessed whether ecological divergence has enhanced the diversification of the Neotropical alpine plant complex Es...


Autor(es): Luz Nayibe Garzon.   Andrés J. Cortés .   Jhon B. Valencia.   Santiago Madriñán.  



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2018

Interspecific variation and genetic relationship among Colombian Lippia sp. based on small ribosomal subunit gene sequence analysis

Six Lippia sp. were subjected to sequence analysis of the small ribosomal subunit (SRS) or 18S rDNA gene (ca. 1530 bp in length) for studying their genetic relationship. A total of nine nucleotide differences distinguished the species-specific SRS haplotypes of L. alba, L. americ...


Autor(es): Francisco Jose Martinez.   Fernando Rondon.   Jorge Luis Fuentes.   Liliana Santamaría-Acevedo.   Cesar Augusto Prada-Medina.   Elena Stashenko.   Morris Levy.   María Mercedes Levy.  



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2017

Colores al vuelo

Con tan sugestivo título, la UIS publicó el que tal vez sea su libro bandera. Presentado al público el pasado 5 de marzo, esta obra ha tomado vuelo entre la comunidad universitaria, y ahora se propone tomarlo entre la comunidad general. Sus autores, vinculados a la Escuela de Bio...


Autor(es): Jose Gregorio Moreno.   Jorge Enrique Avendaño.   Fernando Rondon.  



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